BioClosure® Sterile Media Bottle Assemblies

  • Animal Derived Ingredient FreeAvailable in five bottle capacities from 125 mL to 2 liter; square PETG bottles
  • Validated sterility assurance of 10-6 via gamma irradiation per ISO 11137 method VDmax 25
  • AdvantaFlex® tubing supplied with plugged end and dip tube to bottom of bottle with angled cut for easy transfer
  • 0.2 um filter for sterile gas venting
  • Custom lengths and configurations available upon request
  • Also available in platinum cured silicone


  • Aseptic Sampling
  • Media/Buffers Storage
  • Sterile Filling
  • Vaccine Production
  • Process R&D


for BioClosure Sterile Media Bottle Assemblies

Product Number Bottle Capacity
AFBA2-38-0012 125 mL
AFBA2-38-0025 250 mL
AFBA2-38-0050 500 mL
AFBA2-38-0100 1000 mL (1 Liter)
AFBA2-53-0200 2000 mL (2 Liter)

All AdvantaFlex BioClosure Sterile Media Bottle Assemblies are supplied with one (1) 1/8″ I.D. x 1/4″ O.D. dip tube line and one (1) 1/4″ I.D. x 7/16″ O.D. vent line.

bottle assembly exploded view

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for Bottles, Flasks and Carboys


bottle assemblies

Made in USA


single use system

Eliminate production stoppages for sterilization, reduce the risk of leaks and contamination, and increase efficiency by incorporating Single-Use manifolds from AdvantaPure. Single Use products simplify cleaning validations—use once and discard.

Each manifold is custom made using platinum-cured, Class VI silicone tubing or AdvantaFlex® TPE tubing, molded fittings, BioClosures, filters, bottles, labels and tracking options, and other components.

Contact an AdvantaPure representative today to discuss your application.