APSPG
Silicone Pump Grade Tubing
AdvantaSil APSPG (AdvantaPure Silicone Pump Grade) is a high-performance, platinum-cured silicone tubing designed for the most demanding peristaltic pump applications in the pharmaceutical and biopharmaceutical industries. Engineered for long-term durability, this translucent tubing provides excellent fluid visibility and consistent performance through repeated pump cycles. Its advanced formulation ensures reliable operation even under continuous compression and release, significantly outlasting standard silicone tubing.
Manufactured in compliance with stringent regulatory standards, AdvantaSil APSPG undergoes comprehensive testing to ensure high-quality performance. It complies with the industry specifications, including USP and ISO standards, and comes with a complete extractable report from BPOG (Biophorum Operations Group).
Key Features & Benefits
- Compliant with <USP> 665 for extractables and leachables
- Translucent for fluid flow visibility
- Special formulation offers long pump life
- Excellent flexibility
- General temperature range -50°F to 400°F (-45°C to 204.4°C)
- Custom lengths, sizes and packaging available
- Extruded, assembled, and packaged in an ISO Class 7 cleanroom
- Available as leak-proof, simple or complex, overmolded connections and tubing
- Smooth surfaces offer uniform fluid flow and resistance to bacteria build-up
- Manufacturing with a focus on sustainability
- Sterilizable by autoclave and gamma-irradiation
- Comprehensive validation package to expedite qualification and validation, including full extractables report (BPOG)
Product Specifications
Measurements
| Part Number | I.D. | Wall | O.D. | Standard Length Available | |||
|---|---|---|---|---|---|---|---|
| in | mm | in | mm | in | mm | ft | |
| APSPG-0031-0156 | 0.031 | 0.79 | 0.063 | 1.59 | 0.156 | 3.97 | 25 |
| APSPG-0063-0188 | 0.063 | 1.59 | 0.063 | 1.59 | 0.188 | 4.76 | 25 |
| APSPG-0125-0250 | 0.125 | 3.18 | 0.063 | 1.59 | 0.250 | 6.35 | 50 |
| APSPG-0188-0313 | 0.188 | 4.76 | 0.063 | 1.59 | 0.313 | 7.94 | 50 |
| APSPG-0250-0375 | 0.250 | 6.35 | 0.063 | 1.59 | 0.375 | 9.52 | 50 |
| APSPG-0250-0438 | 0.250 | 6.35 | 0.094 | 2.38 | 0.438 | 11.11 | 50 |
| APSPG-0250-0500 | 0.250 | 6.35 | 0.125 | 3.18 | 0.500 | 12.70 | 50 |
| APSPG-0313-0500 | 0.313 | 7.94 | 0.094 | 2.38 | 0.500 | 12.70 | 50 |
| APSPG-0375-0563 | 0.375 | 9.52 | 0.094 | 2.38 | 0.563 | 14.29 | 50 |
| APSPG-0375-0625 | 0.375 | 9.52 | 0.125 | 3.18 | 0.625 | 15.88 | 50 |
| APSPG-0500-0750 | 0.500 | 12.70 | 0.125 | 3.18 | 0.750 | 19.05 | 50 |
Physical Properties
| ASTM Method | Value | |
|---|---|---|
| Durometer, Shore A | D2240 | 50A |
| Specific Gravity | D792 | 1.12 |
| Ultimate Tensile, psi | D412 | 1100 |
| Ultimate Elongation, % | D412 | 450 |
| Tensile Modulus @100%, psi | D412 | 200 |
| Tear Strength, Die B, ppi | D624 | 100 |
| Compression Set, % | D395B | 30 |
Compliant or tested to
- BPOG Extractables/Leachables
- USP <87> Cytotoxicity MEM Elution
- USP <88> Class VI
- USP <85> Bacterial Endotoxin
- European Pharmacopeia 3.1.9
- ISO 10993-3 (Ames Genotoxicity)
- RoHS Compliant
- ADCF Compliant
Review the Regulatory Overview chart
Chemical Compatibility
| Acids, Dilute / Weak | Test Before Using |
| Acids, Strong / Concentrated | Test Before Using |
| Bases, Dilute / Weak | Acceptable |
| Bases, Strong / Concentrated | Test Before Using |
| Salts | Acceptable |
| High Purity Water | Test Before Using |
| Oil/Water Emulsion | Test Before Using |
| Alcohol | Test Before Using |
| Organic Solvent | Test Before Using |
Sterility
Available with validated sterility assurance of 10-6 via gamma irradiation per ISO 11137 method VDmax 25. A full sterility validation guide is available upon request.
Sterilization Methods
| Autoclave | One-time cycle at 121°C, 30 min |
| Gamma Irradiation | One-time up to 40 kGy |
Typical Applications
Extended Pump Life
Bioreactor Process Lines
Separation and Purification
Chromatograhy
Liquid Dispensing and Filling
Cell Culture and Harvest
Media Preparation
Filtration and Fermentation
Ideal for use in assembies and bag manifolds
Download a printable version of our AdvantaSil APSPG brochure
Suggested Additional Components
Molded
Ends
All AdvantaSil APSPG sizes can be integrated into our assemblies and manifolds. Choose standardly available wyes, tees, sanitary ends, intersections, and reducers, or opt for our custom overmolding design services to create custom pieces for your unique application.
Overmolding - Connections and Assemblies
Ideal for aseptic transfer and processing, overmolded with multi-tube TC’s and sanitary ends to form a smooth fluid path.
Bioreactor
Tubing Kits
Built-to-order in an ISO Class 7 cleanroom, assembled with various components for convenience and efficiency.
Sterile Bottle Assemblies
Provide a ready-to-use, cost-effective solution for aseptic sampling, cell growth, and filling application. The robust molded closure design features a continuous flow path.