request validation Single Use Systems (SUS)

Single-Use / Disposable Process Systems For Pharmaceutical & Biotech Processing Applications

single use systemEliminate production stoppages for sterilization, reduce the risk of contamination, and increase efficiency by incorporating Single-Use Systems from AdvantaPure. Single Use Systems, or SUS, simplify cleaning validations—use once and discard.

Each system is custom made using platinum-cured, Class VI silicone tubing and hose or AdvantaFlex® Class VI biopharmaceutical grade tubing for peristaltic pump applications. Add fittings, stoppers and container closures, filters, bottles, labels and tracking options, and other components.

Single use systems are not intended for implantation or continuous steam applications.

KEY FEATURES


BUILD YOUR SYSTEM FROM:

silicone tubing and hoseSilicone Tubing and Hose

animal derived indgediantsLow-volatile grade, platinum-cured silicone tubing and braid-reinforced silicone hose is clean-room manufactured by AdvantaPure for pharmaceutical and biotech applications.

Both the tubing (called APST) and hose (APSH) have undergone extensive physical, chemical, and biological testing and meet USP Class VI, FDA CFR 177.2600, ISO 10993, European Pharmacopoeia 3.1.9, and 3-A standards. Certified free of animal-derived ingredients.

APST size range: .030" through 1" I.D. (.76mm through 25.40mm I.D.)
APSH size range: .063" through 1" I.D. (1.59mm through 25.40mm I.D.)


AdvantaFlex Biopharmaceutical Grade TubingAdvantaFlex® BioPharmaceutical Grade Tubing

animal derived indgediantsAdvantaFlex addresses the need for a flexible, translucent, sterilizable, heat sealable, weldable and moldable biopharmaceutical tubing for fluid processing. The unique properties of AdvantaFlex help it outlast similar tubing tested in peristaltic pumps by 6-10 times.

AdvantaFlex is ideal for aseptic tubing welds, as it eliminates costly aseptic connectors and multiple contact surfaces. The tubing is made from FDA-approved ingredients and meets various ISO and USP standards, including Class VI, as well as European Pharmacopoeia 3.2.2.1 standards. Certified free of animal-derived ingredients.

Size range: 1/8" to 1" I.D. (3.18mm to 25.40mm I.D.)

MORE ABOUT ADVANTAFLEX

 

BACK TO TOP

 


BUILD YOUR SYSTEM FROM:

molded silicone manifoldsMolded Manifolds

animal derived indgediantsSingle-use Molded Manifolds provide a seamless transition between tubing and connections for a continuous, leak-proof flow. Molded connections include Y, T, cross, reducer, Tri-Clamp®, and mini Tri-Clamp styles. Made from platinum-cured silicone or AdvantaFlex biopharmaceutical grade TPE, they allow for one material contact surface throughout the system. Connections sizes differ depending on style. Certified free of animal-derived ingredients.

Size range: .188" to 1" I.D. (4.76mm to 25.40mm I.D.)

MORE ABOUT MOLDED MANIFOLDS

Leak Free Molded Manifold Connections


tubing setTubing Sets

If you're not sure molded manifolds are right for your application, let us manu- facture your tubing sets (line sets). Assembled in Class 7, ISO-certified clean rooms, they're fabricated from tubing, fittings and accessories you specify.

Sizes to 1" I.D.

 

 

 


bioreactor tubingBioreactor Tubing Kits

The Single-Use kits are custom manufactured and assembled from a variety of components — tubing, filters, connectors — to meet your needs. Made from platinum-cured silicone or AdvantaFlex® biopharmaceutical grade TPE tubing, AdvantaPure's Bioreactor Tubing Kits provide convenience and greater efficiency.

MORE ABOUT BIOREACTOR TUBING KITS

 

 

BACK TO TOP

 


BUILD YOUR SYSTEM FROM:

BioClosure True Union AssemblyBioClosure® Systems - High Purity Container Closures

animal derived indgediantsAdvantaPure's BioClosure Systems offer purity, secure seals, and versatility in design. Stoppers, caps, True Union and GL45 inserts, and other styles, available with or without tubing inserts, are manufactured from platinum-cured, Class VI silicone or AdvantaFlex biopharmaceutical TPE. Certified free of animal-derived ingredients.

MORE ABOUT BIOCLOSURE® HIGH PURITY CONTAINER CLOSURES

Bioclosure products   Bioclosure products


BioClosure System AssembliesBioClosure System Assemblies

animal derived indgediantsStandardized configurations for media bottles, flasks and carboys using AdvantaFlex Biopharmaceutical Grade TPE tubing and molded components are available.

MORE ABOUT BIOCLOSURE SYSTEM ASSEMBLIES

 

 

BACK TO TOP

 


BUILD YOUR SYSTEM FROM:

Connections
ThermoBarb Plastic FittingBarbed Fittings
come in Y, T, elbow, and reducer styles. Materials include polypropylene, polyethylene, and PVDF.

Size range: 1/8" to 1" hose I.D. (3.18mm to 25.40mm hose I.D.)

Overmolded EndsOvermolded Ends
are available in mini Tri-Clamp styles in AdvantaFlex TPE for a smooth fluid path.

Size range: 1/8" to 1/2" tubing I.D. (3.18mm to 12.70mm tubing I.D.)


Aseptic ConnectorsAseptic Connectors
reduce contamination risks and keep processing systems pure. Several easy-to-use styles are available.

Quick ConnectsQuick Connects
offer on-the-spot connections and come in several materials. Dependable and secure.

Filters
filtersChoose from a variety of styles, sizes, and manufacturers for your single use system.
Sensors
sensor assemblySingle-Use in-line sensors offer real- time monitoring and control of critical processes. They eliminate the need for cleaning, maintenance and recali- bration associated with traditional, reusable technologies. Choose from sensors for pressure, flow, temperature, conductivity, turbidity and UV absorbance.
Tubing-to-Fitting Attachments
cable tiesCable Ties
are quick and easy to apply; no tools are needed. For added security, it is recommended that two ties be used at each attachment.

Oetiker ClampsOetiker® Clamps
provide a 360° seal with both a smooth inner and outer surface. Made from stainless steel, Oetiker clamps are lightweight and compact yet robust—only one is needed at each attachment.

Size range: 5/32" to 1-9/16" nominal tubing O.D.

Clamps
pinch clampsPinch Clamps
squeeze tubing closed anywhere along a line. One piece construction for sizes fit up to 3/4" tubing O.D. (19.05mm tubing O.D.) Vise clamp for tubing 1" and larger

Tri-Clover ClampsTri-Clamp® Connection Clamps
come in durable plastic and 304 stainless steel.

Size range: 1/2" to 4" (12.70mm to 101.60mm), depending on material

 


PDF Download a printable version of our Single-Use Process Systems brochure. Single_Use_Systems.pdf (828KB)

 

BACK TO TOP

BUILD YOUR SYSTEM FROM:

Made in USA

INTRODUCING
AdvantaPass logo

CLEAN ROOM
PASS-THROUGH
TECHNOLOGY

AdvantaTube Sealer

OPTIONS

DocuLink Manifold Identification System

DocuLink® - Manifold Identification System

DocuLink is our new silicone manifold identification system providing individual identification and tracking information directly on each manifold in the form of a silicone-encased label. Manifold information can be linked to an on-line data management site to provide easy document retrieval for audits and validations. READ MORE...


gamma irradiation services

Gamma Irradiation Services

Have your single use system gamma irradiated before it arrives at your location and save the additional inventorying, transportation costs, and transit time.

Bagged and labeled products are picked up from AdvantaPure's facility and conveyed to a local gamma irradiation service provider. Using Cobalt 60 radiation, microorganisms and bacteria are destroyed while your single use system remains in its original packaging. Products are then returned to AdvantaPure for final inspection and shipment to your location.

A number of AdvantaPure's silicone and AdvantaFlex products, particularly those designed for single use, are available with validated sterility assurance of 10-6 per ISO 11137 method VDmax. Contact us for more information at 1-888-755-4370.

White Papers

Our Sustainablility

SUSDocs.org

feedback and suggestions


| Home | Products | News & Events | About Us | Find a Distributor | Information Request | Contact Us |
| Tubing & Hose | Fittings | Single-Use Systems | Molded Products | Custom Products & Services | Hose Identification | Product Videos |
| Legal Notices & Trademarks | Terms & Conditions of Sale | Privacy Policy | Feedback/Questions | Site Map |

facebook    linkedin    google plus    youtube