Phone: 1-888-755-4370 (toll free US only)
Phone: 1-215-526-2151 (worldwide)
Eliminate production stoppages for sterilization, reduce the risk of contamination, and increase efficiency by incorporating Single-Use Systems from AdvantaPure. Single Use Systems, or SUS, simplify cleaning validations—use once and discard.
Each system is custom made using platinum-cured, Class VI silicone tubing and hose or AdvantaFlex® Class VI biopharmaceutical grade tubing for peristaltic pump applications. Add fittings, stoppers and container closures, filters, bottles, labels and tracking options, and other components.
Single use systems are not intended for implantation or continuous steam applications.
Both the tubing (called APST) and hose (APSH) have undergone extensive physical, chemical, and biological testing and meet USP Class VI, FDA CFR 177.2600, ISO 10993, European Pharmacopoeia 3.1.9, and 3-A standards. Certified free of animal-derived ingredients.
AdvantaFlex addresses the need for a flexible, translucent, sterilizable, heat sealable, weldable and moldable biopharmaceutical tubing for fluid processing. The unique properties of AdvantaFlex help it outlast similar tubing tested in peristaltic pumps by 6-10 times.
AdvantaFlex is ideal for aseptic tubing welds, as it eliminates costly aseptic connectors and multiple contact surfaces. The tubing is made from FDA-approved ingredients and meets various ISO and USP standards, including Class VI, as well as European Pharmacopoeia 126.96.36.199 standards. Certified free of animal-derived ingredients.
Size range: 1/8" to 1" I.D. (3.18mm to 25.40mm I.D.)
Single-use Molded Manifolds provide a seamless transition between tubing and connections for a continuous, leak-proof flow. Molded connections include Y, T, cross, reducer, Tri-Clamp®, and mini Tri-Clamp styles. Made from platinum-cured silicone or AdvantaFlex biopharmaceutical grade TPE, they allow for one material contact surface throughout the system. Connections sizes differ depending on style. Certified free of animal-derived ingredients.
Size range: .188" to 1" I.D. (4.76mm to 25.40mm I.D.)
If you're not sure molded manifolds are right for your application, let us manu- facture your tubing sets (line sets). Assembled in Class 7, ISO-certified clean rooms, they're fabricated from tubing, fittings and accessories you specify.
Sizes to 1" I.D.
The Single-Use kits are custom manufactured and assembled from a variety of components — tubing, filters, connectors — to meet your needs. Made from platinum-cured silicone or AdvantaFlex® biopharmaceutical grade TPE tubing, AdvantaPure's Bioreactor Tubing Kits provide convenience and greater efficiency.
AdvantaPure's BioClosure Systems offer purity, secure seals, and versatility in design. Stoppers, caps, True Union and GL45 inserts, and other styles, available with or without tubing inserts, are manufactured from platinum-cured, Class VI silicone or AdvantaFlex biopharmaceutical TPE. Certified free of animal-derived ingredients.
come in Y, T, elbow, and reducer styles. Materials include polypropylene, polyethylene, and PVDF.
Size range: 1/8" to 1" hose I.D. (3.18mm to 25.40mm hose I.D.)
Size range: 1/8" to 1/2" tubing I.D. (3.18mm to 12.70mm tubing I.D.)
reduce contamination risks and keep processing systems pure. Several easy-to-use styles are available.
|Choose from a variety of styles, sizes, and manufacturers for your single use system.|
|Single-Use in-line sensors offer real- time monitoring and control of critical processes. They eliminate the need for cleaning, maintenance and recali- bration associated with traditional, reusable technologies. Choose from sensors for pressure, flow, temperature, conductivity, turbidity and UV absorbance.|
are quick and easy to apply; no tools are needed. For added security, it is recommended that two ties be used at each attachment.
provide a 360° seal with both a smooth inner and outer surface. Made from stainless steel, Oetiker clamps are lightweight and compact yet robust—only one is needed at each attachment.
Size range: 5/32" to 1-9/16" nominal tubing O.D.
squeeze tubing closed anywhere along a line. One piece construction for sizes fit up to 3/4" tubing O.D. (19.05mm tubing O.D.) Vise clamp for tubing 1" and larger
Tri-Clamp® Connection Clamps
Download a printable version of our Single-Use Process Systems brochure. Single_Use_Systems.pdf (828KB)
BUILD YOUR SYSTEM FROM:
DocuLink is our new silicone manifold identification system providing individual identification and tracking information directly on each manifold in the form of a silicone-encased label. Manifold information can be linked to an on-line data management site to provide easy document retrieval for audits and validations. READ MORE...
Have your single use system gamma irradiated before it arrives at your location and save the additional inventorying, transportation costs, and transit time.
Bagged and labeled products are picked up from AdvantaPure's facility and conveyed to a local gamma irradiation service provider. Using Cobalt 60 radiation, microorganisms and bacteria are destroyed while your single use system remains in its original packaging. Products are then returned to AdvantaPure for final inspection and shipment to your location.
A number of AdvantaPure's silicone and AdvantaFlex products, particularly those designed for single use, are available with validated sterility assurance of 10-6 per ISO 11137 method VDmax. Contact us for more information at 1-888-755-4370.