request validation Single Use Systems (SUS)

Single-Use / Disposable Process Systems For Pharmaceutical & Biotech Processing Applications

Eliminate production stoppages for sterilization, reduce the risk of contamination, and increase efficiency by incorporating single use systems from AdvantaPure. Single use systems, or SUS, simplify cleaning validations—use once and discard.

Each system is custom made using platinum-cured, Class VI silicone tubing and hose or AdvantaFlex® Class VI biopharmaceutical grade tubing for peristaltic pump applications. Add fittings, stoppers and container closures, filters, bags, bottles, labels and tracking options, and other components.

Single use systems are not intended for implantation or continuous steam applications.

KEY FEATURES


BUILD YOUR SYSTEM FROM:

silicone tubing and hoseSilicone Tubing and Hose

animal derived indgediantsLow-volatile grade, platinum-cured silicone tubing and braid-reinforced silicone hose is clean-room manufactured by AdvantaPure for pharmaceutical and biotech applications.

Both the tubing (called APST) and hose (APSH) have undergone extensive physical, chemical, and biological testing and meet USP Class VI, FDA CFR 177.2600, ISO 10993, European Pharmacopoeia 3.1.9, and 3A standards.

APST size range: .030" through 1" I.D. (.76mm through 25.40mm I.D.)
APSH size range: .063" through 1" I.D. (1.59mm through 25.40mm I.D.)


AdvantaFlex Biopharmaceutical Grade TubingAdvantaFlex® BioPharmaceutical Grade Tubing

animal derived indgediantsAdvantaFlex addresses the need for a flexible, translucent, sterilizable, heat sealable, weldable and moldable biopharmaceutical tubing for fluid processing. The unique properties of AdvantaFlex help it outlast similar tubing tested in peristaltic pumps by 6-10 times.

AdvantaFlex is ideal for aseptic tubing welds, as it eliminates costly aseptic connectors and multiple contact surfaces. The tubing is made from FDA-approved ingredients and meets various ISO and USP standards, including Class VI, as well as European Pharmacopoeia 3.2.2.1 standards.

Size range: 1/8" to 1" I.D. (3.18mm to 25.40mm I.D.)

MORE ABOUT ADVANTAFLEX

 

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BUILD YOUR SYSTEM FROM:

molded silicone manifoldsMolded Manifolds

animal derived indgediantsSingle-use Molded Manifolds provide a seamless transition between tubing and connections for a continuous, leak-proof flow. Molded connections include Y, T, cross, reducer, Tri-Clamp®, and mini Tri-Clamp styles. Made from platinum-cured silicone or AdvantaFlex biopharmaceutical grade TPE, they allow for one material contact surface throughout the system. Connections sizes differ depending on style.

Size range: .188" to 1" I.D. (4.76mm to 25.40mm I.D.)

MORE ABOUT MOLDED MANIFOLDS

Leak Free Molded Manifold Connections

 

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BUILD YOUR SYSTEM FROM:

BioClosure True Union AssemblyBioClosure® Systems - High Purity Container Closures

animal derived indgediantsAdvantaPure's BioClosure Systems offer purity, secure seals, and versatility in design. Stoppers, caps, True Union and GL45 inserts, and other styles, available with or without tubing inserts, are manufactured from platinum-cured, Class VI silicone or AdvantaFlex biopharmaceutical TPE.

MORE ABOUT BIOCLOSURE® HIGH PURITY CONTAINER CLOSURES

Bioclosure products   Bioclosure products

 

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BUILD YOUR SYSTEM FROM:

Connections
ThermoBarb Plastic FittingBarbed Fittings
come in Y, T, elbow, and reducer styles. Materials include polypropylene, polyethylene, and PVDF.

Size range: 1/8" to 1" hose I.D. (3.18mm to 25.40mm hose I.D.)

Overmolded EndsOvermolded TriClamp Ends
are available in Tri-Clamp and mini Tri-Clamp styles in Hytrel® and polypropylene materials.

Size range: 1/8" to 1-3/16" hose I.D. (3.18mm to 30.16mm hose I.D.)


AdvantaFlex MoldedAseptic ConnectorsAseptic Connectors
reduce contamination risks and keep processing systems pure. Several easy-to-use styles are available. AdvantaFlex tubing can even be molded onto connectors (patent pending), reducing the risk of leaks associated with barbed fittings and eliminating cable ties and their risk of piercing bags or packaging.
Note: Molding onto aseptic connectors and filters may involve R&D and lengthy lead times; call for details.

Quick ConnectsQuick Connects
offer on-the-spot connections and come in several materials. Dependable and secure.

Clamps
pinch clampsPinch Clamps
of polypropylene or polyester squeeze tubing closed anywhere along a line. One piece construction.

Sizes fit up to 3/4" tubing O.D. (19.05mm tubing O.D.)

Tri-Clover ClampsTri-Clamp Connection Clamps
come in 304 stainless steel and durable plastic.

Size range: 1/2" to 4" (12.70mm to 101.60mm), depending on material

Filters
AdvantaFlex MoldedfiltersChoose from a variety of styles, sizes, and manufacturers for your single use system. Like aseptic connectors, AdvantaFlex tubing may be molded onto filters (patent pending), reducing the risk of leaks asso- ciated with barbed fittings and eliminating cable ties and their risk of piercing bags or packaging.
Note: Molding onto aseptic connectors and filters may involve R&D and lengthy lead times; call for details.
Bags
bagsAdvantaPure can supply bags from a number of leading manufacturers. Let us know what you need.
Bottles
bottlesLaboratory and sampling bottles can also be incorporated into your system. Select from HDPE and other materials. For stoppers and container closures, see our BioClosure® Systems.

 


PDF Download a printable version of our Single-Use Process Systems brochure. Single_Use_Systems.pdf (828KB)

 

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single use system

BUILD YOUR SYSTEM FROM:

 

Made in USA

 

product videos

 

AdvantaTube Sealer

 

OPTIONS

DocuLink Manifold Identification System

DocuLink® - Manifold Identification System

DocuLink is our new silicone manifold identification system providing individual identification and tracking information directly on each manifold in the form of a silicone-encased label. Manifold information can be linked to an on-line data management site to provide easy document retrieval for audits and validations. READ MORE...


gamma irradiation services

Gamma Irradiation Services

Have your single use system gamma irradiated before it arrives at your location and save the additional inventorying, transportation costs, and transit time.

Bagged and labeled products are picked up from AdvantaPure's facility and conveyed to a local gamma irradiation service provider. Using Cobalt 60 radiation, microorganisms and bacteria are destroyed while your single use system remains in its original packaging. Products are then returned to AdvantaPure for final inspection and shipment to your location.

A number of AdvantaPure's silicone and AdvantaFlex products, particularly those designed for single use, are available with validated sterility assurance of 10-6 per ISO 11137 method VDmax. Contact us for more information at 1-888-755-4370.

 

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