Validations Request AdvantaFlex®: Biopharmaceutical Grade TPE Tubing

Sterile Weldable, Heat Sealable Bioprocess Tubing

AdvantaFlex Biopharmaceutical Tubing   There is a Better Alternative

AdvantaFlex heat sealAdvantaFlex addresses the need for a flexible, translucent, sterilizable, moldable, heat sealable, and weldable biopharmaceutical tubing for fluid processing. AdvantaFlex TPE tubing maintains its physical properties following sterilization processes, resists kinking, remains translucent for visible product flow, and does not become gummy.

KEY FEATURES

There is a Better Alternative
Discover how much better the right tubing — AdvantaFlex — will work in
your pharmaceutical, biotech, medical, or other critical processing application.

 

 


APPLICATIONS

Because of its ability to be sealed and welded, AdvantaFlex is ideal for filling and sampling applications.

There is a Better Alternative

 


SPECIFICATIONS

ADVANTAFLEX® - BIOPHARMACEUTICAL GRADE TPE

AdvantaFlex Biopharmaceutical TPE tubing
Part
Number
I.D.
Wall
(reference)
O.D.
Working Pressure
at 70°F (21.1°C)
Standard Lengths
Coiled

Standard Lengths
on Spools

  (in.) (mm.) (in.) (mm.) (in.) (mm.) PSI Bar (ft.) (ft.)
APAF-BP-0125-0250 .125 3.18 .062 1.57 .250 6.35 30 2.1 50, 100 500
APAF-BP-0188-0313 .188 4.76 .062 1.57 .313 7.94 23 1.6 50, 100 -
APAF-BP-0188-0375 .188 4.76 .094 2.38 .375 9.52 32 2.2 50, 100 350
APAF-BP-0250-0375 .250 6.35 .063 1.59 .375 9.52 20 1.4 50, 100 -
APAF-BP-0250-0438 .250 6.35 .094 2.38 .438 11.11 23 1.6 50, 100 300
APAF-BP-0250-0500 .250 6.35 .125 3.18 .500 12.70 30 2.1 50, 100 -
APAF-BP-0313-0438 .313 7.94 .062 1.57 .438 11.11 21 1.4 50, 100 300
APAF-BP-0313-0500 .313 7.94 .094 2.38 .500 12.70 24 1.6 50, 100 -
APAF-BP-0375-0500 .375 9.52 .062 1.57 .500 12.70 18 1.3 50, 100 -
APAF-BP-0375-0563 .375 9.52 .094 2.39 .563 14.30 23 1.6 50 -
APAF-BP-0375-0625 .375 9.52 .125 3.18 .625 15.88 24 1.6 50, 100 150
APAF-BP-0500-0750 .500 12.70 .125 3.18 .750 19.09 22 1.5 50, 100 100
APAF-BP-0625-0875 .625 15.88 .125 3.18 .875 22.23 18 1.3 50, 100 -
APAF-BP-0750-1000 .750 19.05 .125 3.18 1.000 25.40 17 1.2 50, 100 75
APAF-BP-0750-1125 .750 19.05 .188 4.76 1.125 28.58 18 1.3 50, 100 50
APAF-BP-1000-1375 1.000 25.40 .188 4.76 1.375 34.93 18 1.3 25 -

Sold by standard lengths only. Add length suffix code to product number when ordering—see the Coil Length Legend at right for length suffix codes. Example: a 50 foot coil of .125 inch I.D. x .250 inch O.D. tubing is product number APAF-BP-0125-0250L. Add length and "S" to denote "spool" for products with lengths available on spools. Example: a 500 foot spool of .125 inch I.D. x .250 inch O.D. tubing is product number APAF-BP-0125-0250-500S. Working pressures are calculated from burst testing using a 3:1 safety factor. Coils and spools are supplied double bagged in heat-sealed polybags and bulk packed. Contact your AdvantaPure Sales Representative for other packaging options.

The data listed throughout this web site is meant only as a guide to aid in design, and is believed to be reliable; however, nothing stated shall constitute a guarantee or warranty for any application. Product field-testing should be performed to find the actual values for a specific application.

Coil Length Legend

P = 25 feet
L = 50 feet
K = 100 feet

 

 

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MOLDED ASSEMBLIES AND CONNECTIONS

  • AdvantaFlex molded connectionsBuild a complete single use system from AdvantaFlex
  • Eliminates the need to splice silicone tubing sections into a process line
  • Reduce the number of barbed fittings and cable ties needed and their potential for contamination, leaks, and a wasted batch of product
  • AdvantaFlex molded connections provide a smooth inner surface for even, unrestricted flow
  • AdvantaFlex MoldedChoose from T's, Y's, reducers, couplers, crosses, mini and standard Tri-Clamps®, BioClosure® container closures and inserts such as GL45's
  • Available with validated sterility assurance of 10-6 via gamma irradiation per ISO 11137 method VDmax 25

 


BioClosure System AssembliesBioClosure System Assemblies

animal derived indgediantsStandardized configurations for media bottles, flasks and carboys using AdvantaFlex Biopharmaceutical Grade TPE tubing and molded components are available.

MORE ABOUT BIOCLOSURE SYSTEM ASSEMBLIES

 


bioreactor tubingBioreactor Tubing Kits

The Single-Use kits are custom manufactured and assembled from a variety of components — tubing, filters, connectors — to meet your needs. Made from platinum-cured silicone or AdvantaFlex® biopharmaceutical grade TPE tubing, AdvantaPure's Bioreactor Tubing Kits provide convenience and greater efficiency.

MORE ABOUT BIOREACTOR TUBING KITS

 

 


 

PDF Download a printable version of our AdvantaFlex brochure. AdvantaFlex.pdf (616kb)

 

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AdvantaFlex TPE Tubing

PHYSICAL PROPERTIES
Specific Gravity .89
Durometer, Shore A ±5 65
Ultimate Tensile Strength, PSI 1000
Ultimate Elongation % 550
Tensile Modulus @ 100%, PSI 410
Tear Strength, Die B, PPI 240
Compression Set, % per ASTM D-395B 25
Max. Operating Temperature, °F 275
Brittle Temperature, °F -88

Made in USA

AdvantaTube®
STERILE WELDER

AdvantaTube Sterile Welder

The AdvantaTube Welder makes sterile tubing welds quickly, reliably, and easily. Developed for biopharmaceutical applications, the AdvantaTube Welder has been designed to optimally work in all AdvantaFlex® TPE tubing applications including wet, dry, or fluid filled tubing. READ MORE...


New
AdvantaTube® Aria
SEALER

New Model

AdvantaTube Sealer

Sealing AdvantaFlex TPE tubing is fast and easy with the AdvantaTube Aria Sealer. It offers a compact design, simple operation, reliability, and portability — the remote sealing head uses an 8 foot cable allowing you to seal at the location that's convenient for you. READ MORE...

 

ALSO AVAILABLE

SEALED TUBING ENDS

Sealed Tubing Ends

Take advantage of the convenience of pre-sealed tubing ends made from AdvantaFlex biopharmaceutical grade TPE, for Single-Use applications such as sampling and storage. Weld a Sealed Tubing End to the tubing from your bag or other container and maintain your sterile, closed system. MORE INFO...


MOLDED TUBING ENDS

Sealed Tubing Ends

Single-Use AdvantaFlex tubing with molded mini Tri-Clamp® ends are ideal for aseptic transfer and processing applications. The TPE tubing is overmolded with a USP Class VI polypropylene mini Tri-Clamp to form a smooth fluid path. Available in a variety of tubing sizes and lengths for your biopharma fluid transfer applications.
MORE INFO...

 

GAMMA IRRADIATION SERVICES

gamma irradiation services

Have your AdvantaFlex single use system gamma irradiated before it arrives at your location and save the additional inventorying, transportation costs, and transit time.

Bagged and labeled products are picked up from AdvantaPure's facility and conveyed to a local gamma irradiation service provider. Using Cobalt 60 radiation, microorganisms and bacteria are destroyed while your single use system remains in its original packaging. Products are then returned to AdvantaPure for final inspection and shipment to your location.

A number of AdvantaPure's silicone and AdvantaFlex products, particularly those designed for single use, are available with validated sterility assurance of 10-6 via gamma irradiation per ISO 11137 method VDmax 25. Contact us for more information at 1-888-755-4370.


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