Made in USA
| PHYSICAL PROPERTIES |
| Specific Gravity |
.89 |
| Durometer, Shore A ±5 |
65 |
| Ultimate Tensile Strength, PSI |
2167 |
| Ultimate Elongation % |
948 |
| Tensile Modulus @ 100%, PSI |
364 |
| Tear Strength, Die B, PPI |
350 |
| Compression Set, Method B, 22 hours @ 23°C at 25% deflection, % |
9.9 |
| Max. Operating Temperature, °F |
275 |
| Brittle Temperature, °F |
-88 |
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Gamma Irradiation Services |
Have your single use system gamma irradiated before it arrives at your location and save the additional inventorying, transportation costs, and transit time.
Bagged and labeled products are picked up from AdvantaPure’s facility and conveyed to a local gamma irradiation service provider. Using Cobalt 60 radiation, microorganisms and bacteria are destroyed while your single use system remains in its original packaging. Products are then returned to AdvantaPure for final inspection and shipment to your location. |
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 A new formulation of TPE (thermoplastic elastomer) tubing has been developed for fluid transfer in the biopharmaceutical industry: AdvantaFlex.
AdvantaFlex addresses the need for a flexible, translucent, sterilizable, moldable, heat sealable, and weldable bio- pharmaceutical tubing for fluid processing. AdvantaFlex maintains its physical properties following sterilization processes, resists kinking, remains translucent for visible product flow, and does not become gummy. Additionally, the unique properties of AdvantaFlex help it outperform similar tubing in peristaltic pumps.
Key Features
- Excellent life in peristaltic pumps
- Sterile weldable and heat sealable
- Now available as leak-proof molded connections and tubing
- Made from FDA-approved ingredients
- Excellent low absorption and adsorption characteristics as compared to silicone
- Meets various ISO and USP standards, including Class VI
- Meets European Pharmacopoeia 3.2.2.1 standards
- Low permeability as compared to silicone
- Certified free of silicone oils and animal-derived ingredients
- Smooth interior for excellent flow and performance
- Sterilizable by gamma radiation or autoclave
- Translucent for fluid flow visibility
- Excellent tubing component for single-use systems
- Sizes from 1/8” (.125) through 1” (1.000) I.D.
- Custom lengths, sizes, and packaging available
- Sealed in polybags at manufacture for cleanliness
- Documented quality control; lot traceable with identification on polybags
- Single resin validation — no need to graft to other tubing materials like silicone for media filling and sampling applications that involve peristaltic pumps; helps eliminate operator errors
- Chemical Characterization of Materials per ISO — “Extractables” test portfolio available
- Complete validation package available upon request
Discover how much better the right tubing — AdvantaFlex — will work
in
your pharmaceutical, biotech, medical, or other critical processing application.
| SPECIFICATIONS |
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ADVANTAFLEX® - BIOPHARMACEUTICAL GRADE TPE |
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| Part |
I.D. |
I.D. |
Wall |
Wall |
O.D. |
O.D. |
Working |
Working |
Standard Length |
| Number |
(in.) |
(mm) |
(in.) |
(mm) |
(in.) |
(mm) |
Pressure* PSI |
Pressure* Bar |
(ft.) |
| APAF-BP-0125-0250 |
.125 |
3.18 |
.063 |
1.59 |
.250 |
6.35 |
30 |
2.1 |
50 |
| APAF-BP-0188-0313 |
.188 |
4.76 |
.063 |
1.59 |
.313 |
7.94 |
23 |
1.6 |
50 |
| APAF-BP-0188-0375 |
.188 |
4.76 |
.094 |
2.38 |
.375 |
9.52 |
32 |
2.2 |
50 |
| APAF-BP-0250-0375 |
.250 |
6.35 |
.063 |
1.59 |
.375 |
9.52 |
20 |
1.4 |
50 |
| APAF-BP-0250-0438 |
.250 |
6.35 |
.094 |
2.38 |
.438 |
11.11 |
23 |
1.6 |
50 |
| APAF-BP-0250-0500 |
.250 |
6.35 |
.125 |
3.18 |
.500 |
12.70 |
30 |
2.1 |
50 |
| APAF-BP-0313-0438 |
.313 |
7.94 |
.063 |
1.59 |
.438 |
11.11 |
21 |
1.4 |
50 |
| APAF-BP-0313-0500 |
.313 |
7.94 |
.094 |
2.38 |
.500 |
12.70 |
24 |
1.6 |
50 |
| APAF-BP-0375-0500 |
.375 |
9.52 |
.063 |
1.59 |
.500 |
12.70 |
18 |
1.3 |
50 |
| APAF-BP-0375-0625 |
.375 |
9.52 |
.125 |
3.18 |
.625 |
15.88 |
24 |
1.6 |
50 |
| APAF-BP-0500-0750 |
.500 |
12.70 |
.125 |
3.18 |
.750 |
19.09 |
22 |
1.5 |
50 |
| APAF-BP-0625-0875 |
.625 |
15.88 |
.125 |
3.18 |
.875 |
22.23 |
18 |
1.3 |
50 |
| APAF-BP-0750-1000 |
.750 |
19.05 |
.125 |
3.18 |
1.000 |
25.40 |
17 |
1.2 |
50 |
| APAF-BP-0750-1125 |
.750 |
19.05 |
.188 |
4.76 |
1.125 |
28.58 |
18 |
1.3 |
50 |
| APAF-BP-1000-1375 |
1.000 |
25.40 |
.188 |
4.76 |
1.375 |
34.93 |
18 |
1.3 |
25 |
Sold by standard coil length; longer standard lengths, such as 100 feet, are available on most sizes. Contact your AdvantaPure Sales Representative for details. Add length suffix code to product number when ordering—see the Coil Length Legend at right for length suffix codes. Example: 50 ft. of .125 in. I.D. x .250 in. O.D. tubing is product number APAF-BP-0125-0250L. Coils are supplied in heat-sealed polybags and bulk packed.
*At 70˚F (21.1˚C)
The data listed throughout this web site is meant only as a guide to aid in design, and is believed to be reliable; however, nothing stated shall constitute a guarantee or warranty for any application. Product field-testing should be performed to find the actual values for a specific application.
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Coil Length Legend
P = 25 feet
L = 50 feet
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| APPLICATIONS |
- Sterile filling
- Vaccine production
- Pharmaceutical sampling and delivery systems
- Peristaltic pump transfer
- Single-use systems
- Bioreactor processes
- Cell media, harvesting, and fermentation
- Pharmaceutical production and processing
- High purity water transfer
- Filtration
Because of its ability to be sealed and welded, AdvantaFlex is ideal for filling and sampling applications.
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| CONNECTION OPTIONS |
 MOLDED CONNECTIONS NOW AVAILABLE!
- Build a complete single use system from AdvantaFlex
- Eliminates the need to splice silicone tubing sections into a process line
- Choose from T's, Y's, reducers, couplers, crosses, mini and standard Tri-Clamps®, and BioClosure™ container closures
CLICK HERE for Information
on Molded Connections
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OVERMOLDED TRI-CLAMP® ENDS
 – A new option for sanitary connections is available . . . overmolded sanitary ends for PVC, TPE, and TPR tubing and hose. Injection molded from USP Class VI Hytrel® or polypropylene, overmolded ends feature Tri-Clamp® and mini Tri-Clamp styles.
CLICK HERE for Information
on Overmolded Ends
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| ADVANTAFLEX ADVANTAGES |
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Excellent weldability and sealability allows leak- free, sterile connections for filling and sampling applications. AdvantaFlex is compatible with all portable welding and heat-sealing equipment.
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AdvantaFlex offers excellent life in peristaltic pumps. |
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Biopharmaceutical Grade TPE Tubing
Click link to download a printable version of our AdvantaFlex brochure. 
