AdvantaSil® APHP High Pressure Silicone Tubing
Request Validation PackageAdvantaSil® APHP High Pressure is a platinum-cured silicone specifically engineered to meet critical pharmaceutical and biopharmaceutical high-pressure applications. Designed for high-volume fluid transfer, APHP stands out as the preferred material due to its higher durometer, providing superior pressure ratings compared to standard unreinforced tubing.
Its translucence allows for clear visibility of fluid flow, making it an excellent choice for precise and efficient operations. APHP is rigorously validated, qualified, manufactured, and released under the most stringent product validation protocols, ensuring the highest quality and reliability.
- Translucent for fluid flow visibility while withstanding higher pressures
- 80A durometer for high pressure applications
- General temperature range -65°F to 400°F (-53.9°C to 204.4°C)
- Custom lengths, sizes, and packaging available
- Excellent for applications that require processing at higher flow rates
- Produced, assembled, and packaged in an ISO Class 7 cleanroom
- Wide range of sizes from 0.125″ to 1.5” (3.18 mm to 38.1 mm) I.D.
- Manufactured with a focus on sustainability
- Comprehensive validation package to expedite qualification and validation.
- Full BPOG standardized and USP 665 extractables test results available on request.
| ASTM Method | Value | |
|---|---|---|
| Durometer, Shore A | D2240 | 80 +/-5 |
| Specific Gravity | D792 | 1.18 |
| Ultimate Tensile Strength, psi (MPa) | D412 | 1250 |
| Ultimate Elongation, % | D412 | 250 |
| Tensile Modulus @100%, psi (MPa) | D412 | 900 |
| Tear Strength, Die B, ppi (kN/M) | D624 | 250 (44) |
NOTE: Testing based on liner only.
| Acids, Dilute / Weak | Test Before Using |
| Acids, Strong / Concentrated | Test Before Using |
| Bases, Dilute / Weak | Acceptable |
| Bases, Strong / Concentrated | Test Before Using |
| Salts | Acceptable |
| High Purity Water | Test Before Using |
| Oil/Water Emulsion | Test Before Using |
| Alcohol | Test Before Using |
| Organic Solvent | Test Before Using |
Available with validated sterility assurance of 10-6 via gamma irradiation per ISO 11137 method VDmax 25. A full sterility validation guide is available upon request.
| Autoclave | One-time cycle at 121°C, 30 min |
| Gamma Irradiation | One-time up to 40 kGy |
| X-Ray | One-time up to 40 kGy |
- USP <665> Extractables/Leachables
- USP <87> Cytotoxicity MEM Elution
- USP <88> Class VI
- USP <85> Bacterial Endotoxin
- European Pharmacopeia 3.1.9
- ISO 10993-5 (Cytotoxicity, In Vitro)
- RoHS Compliant
- ADCF Compliant
AdvantaSil High Pressure Unreinforced Silicone Tubing
How to Cut APHP High Pressure Silicone Tubing
ATTENTION: Specific cutting techniques are strongly recommended for AdvantaSil APHP High Pressure Silicone Tubing. APHP must be cut with a chevron style cutter at a 90 degree angle to the tubing, leaving a smooth, non-jagged, perpendicular cut at the tubing end. View cutter product details and purchase information at https://www.lislecorp.com/specialty-tools/hose/hose-cutter. See our cutting technique video below.
Options & Sizes
APHP - HIGH PRESSURE SILICONE TUBING
| Part Number | Catalog Number | I.D. | Wall | O.D. | Working Pressure 3:1 Safety Factor 70°F (21.1°C) | Bend Radius | Vacuum Capability | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| in | mm | in | mm | in | mm | PSI | Bar | in | mm | in.Hg | ||
| A7040521 | APHP-0125-0250 | 0.125 | 3.18 | 0.063 | 1.60 | 0.250 | 6.35 | 58 | 4.0 | 0.375 | 9.5 | >29.5 |
| A7040553 | APHP-0250-0375 | 0.250 | 6.35 | 0.063 | 1.60 | 0.375 | 9.52 | 36 | 2.5 | 1 | 25 | >29.5 |
| A7040852 | APHP-0375-0625 | 0.375 | 9.52 | 0.125 | 3.18 | 0.625 | 15.88 | 56 | 3.9 | 1.2 | 30 | >29.5 |
| A7041086 | APHP-0500-0750 | 0.500 | 12.70 | 0.125 | 3.18 | 0.750 | 19.05 | 41 | 2.8 | 1.8 | 46 | >29.5 |
| A7041463 | APHP-0750-1000 | 0.750 | 19.05 | 0.125 | 3.18 | 1.000 | 25.40 | 34 | 2.3 | 2.1 | 53 | >29.5 |
| A7041684 | APHP-1000-1375 | 1.000 | 25.40 | 0.188 | 4.76 | 1.375 | 34.93 | 25 | 1.7 | 4.1 | 104 | >29.5 |
| A7041834 | APHP-1500-1875 | 1.500 | 38.10 | 0.188 | 4.76 | 1.875 | 47.60 | 27 | 1.9 | 6 | 152 | >29.5 |
NOTE: Not all standard part numbers are stocked items. For the up-to-date list of stocked sizes and lengths available, please contact your sales representative.
Non-listed sizes and custom lengths are available by special order. Working pressures are calculated from burst testing using a 3:1 safety factor. Application testing is recommended. Coils and spools are supplied double-bagged in heat-sealed polybags and bulk packed. Contact your AdvantaPure sales representative for other packaging options.
Specific cutting techniques are strongly recommended for APHP. The tubing must be cut with a chevron style cutter at a 90-degree angle to the tubing.
NOTE: The data listed throughout this datasheet is meant only as a guide to aid in the design and is believed to be reliable; however, nothing stated shall constitute a guarantee or warranty for any application. Product field testing should be performed to find the actual values for a specific application
APHP CASE STUDY AVAILABLE
Using AdvantaSil® High Pressure Unreinforced Silicone Tubing for Bulk Fluid Transfer: The objective of this case study was to identify tubing that would minimize the time required for fluid transfer by maximizing flow rate. The capability of the tubing to withstand pumping flow rates between 5 to 50 LPM and resultant changes in pressure drop until the point of failure (tubing collapse) at the suction line was studied. This case study describes the performances of AdvantaSil High Pressure unreinforced Silicone Tubing (APHP) used in a Monocolonal Antibody process for transfer of buffers in purification.
Download a PDF of our High Pressure Tubing brochure.
