Molded Products
One Stop Shop for Success
Molding is a key capability within AdvantaPure’s manufacturing operations. Our single-use molded components are produced using precision injection molding and overmolding techniques to create seamless, leak-free connections that reduce the need for barbs, fittings, and clamps. These single-use components can be ordered in a variety of custom configurations.
AdvantaPure has what you need for all things molded
Molded Manifolds
Single-Use Assemblies
BioClosure® Systems
Molded Sanitary Ends
Key Benefits
- Enhanced Sterility and Contamination Control
- Reduces the need for components like barbed fittings and hose clamps
- Creates a more seamless flow path, reducing dead spaces and potential microbial
ingress points - Ideal for aseptic operations such as media and buffer preparation, sterile filtration, and final fill
- Reduced Assembly Errors
- Molded configurations minimize time and labor associated with manual fabrication.
- Increases product consistency and manufacturing repeatability
- Reduces chances of incorrect installation during setup, improving operator safety and process repeatability on the drug manufacturing floor
- Accelerated Installation and Turnaround
- Plug-and-play designs simplify equipment setup, enabling rapid changeovers in multi-product facilities
- Improved Integrity and Validation
- Overmolded joints are leak-proof and pressure-tested, reducing the risk of batch loss
- Smoother inner bores reduce cell shear and entrapment, to improve cell viability
- Customized configurations for specific applications based
on user requirements such as:- Upstream: Feed line manifolds for media or buffer delivery and drug substance.
- Downstream: Sample collection or pooling manifolds in filtration or purification steps.
- Final fill: Sterile filling manifolds with multiple filling needles or vessels.
Simplifying Single-Use Solutions with Molded Manifolds
From 37 Components to One
From Hours to Minutes.
Preassembled molded manifolds cut build time, reduce human error, and streamline quality control. One part replaces many — faster, safer, easier.
The traditional assembly on the left is made from: nine pieces of tubing, four barbed fittings, and double cable
ties.
An AdvantaPure overmolded fluid transfer system
is a complete unit. Leaks, entrapment, and
contamination concerns involved with barbed
fitting connections are eliminated.
Seamless Flow, Cleaner Process
No barbs, No Clamps, No Crevices Allowed.
Molded Manifolds have an uninterrupted flow path which eliminates leaks and liquid entrapment as well as eliminates contamination and cell shearing from hose barb impact
Molded Manifold Specifications
| Configuration | Size Range | |
|---|---|---|
| Y CONNECTOR |  |
0.125 inch ID x 0.250 inch OD (3.18 mm ID x 6.35 mm OD) – 1 inch ID x 1.405 inch OD (25.40 mm ID x 35.69 mm OD) |
| T CONNECTOR |  |
0.063 inch ID x 0.188 inch OD (1.60 mm ID x 4.78 mm OD) – 0.625 inch ID x 0.990 inch OD (15.88 mm ID x 25.15 mm OD) |
| CROSS |  |
0.125 inch ID x 0.250 inch OD (3.18 mm ID x 6.35 mm OD) – 0.625 inch ID x 0.875 inch OD (15.88 mm ID x 22.23 mm OD) |
| REDUCER CONNECTOR |  |
0.125 inch ID x 0.250 inch OD (3.18 mm ID x 6.35 mm OD) – 0.750 inch ID x 1 inch OD
(19.05 mm ID x 25.40 mm OD) Various size combinations within this range are available; call for details. |
| TRI-CLAMP® |  |
0.188 inch ID x 0.375 inch OD (4.78 mm ID x 9.53 mm OD) – 1 inch ID x 1.405 inch OD (25.40 mm ID x 35.69 mm OD) Available with polysulfone or stainless steel backing cups. |
| MINI TRI-CLAMP® |  |
0.125 inch ID x 0.250 inch OD (3.18 mm ID x 6.35 mm OD) – 0.500 inch ID x 0.875 inch OD (12.70 mm ID x 22.23 mm OD) |
Download a printable version of our Molded Manifold brochure -PLACEHOLDER
Level Up Your Assemblies
AdvantaPure has the capabilities to help you elevate your next project.
Molded
Products
PUPSIT
Assemblies
Final Fill/
Bulk Filling
Library of Components
BioClosure® Container Systems