Press Release

October 30, 2018 — For Immediate Release

Ultra Low Temp Silicone TubingAdvantaPure® Introduces AdvantaSil™ Ultra Low Temperature Silicone Tubing Engineered for Temperatures as Low as -112°C

Southampton, PA — A new product is available from AdvantaPure: AdvantaSil Ultra Low Temperature Silicone Tubing. This platinum-cured tubing is designed for Single-Use, cold temperature applications in biopharm and pharmaceutical processing such as bulk drug storage and transport.

AdvantaSil Ultra Low Temperature Silicone Tubing offers a solution to the challenge of safeguarding today’s high-value drug products. AdvantaSil Ultra Low Temperature tubing is the first commercially-available silicone tubing engineered to withstand flexing and manipulation within a ‑86°C (‑122.8°F) freezer. Flex and crush testing conducted on gamma-irradiated tubing showed no cracking or loss of integrity – see the video. The tubing has also undergone drop and storage testing. “Customers have been asking for this,” noted Gregg Donovan, AdvantaPure Product Manager. “They need tubing they can have confidence in – a product they know won’t break down or crack in the extremely low temperatures used for cell, drug and media storage and sampling. AdvantaSil Ultra Low Temp was designed specifically for these types of applications.”

Other features include:

  • Meets USP Class VI, FDA CFR 177.2600, ISO 10993, and European Pharmacopeia 3.1.9 standards
  • Optimizes freezer utilization – no protective clam shell is needed for the tubing
  • Available as bulk tubing, molded manifold tubing assemblies, BioClosure® container closures with tubing, or as part of a bag assembly
  • General temperature range: ‑112°C to 175°C (‑169.6°F to 347°F)
  • Sterilizable by autoclave or gamma irradiation
  • Certified free of animal-derived ingredients
  • Documented quality control per ISO 9001:2015
  • Full BPOG standardized extractables test protocol is in process

Ultra Low Temp Silicone Tubing with BioClosureUltra Low Temp Silicone Tubing with Molded Connectors

AdvantaSil Ultra Low Temperature Silicone Tubing is offered in five sizes ranging from 1/8″ through 1/2″ I.D. Single-Use assemblies with molded tees, wyes, crosses and reducer connectors are available through custom order, as are bag assemblies and container closures. Gamma irradiated tubing and assemblies are also available.

For more information on AdvantaSil Ultra Low Temperature Silicone Tubing, visit or contact the AdvantaPure team at 145 James Way, Southampton, PA 18966; phone 888-755-4370 or 215-526-2151; fax 888-258-4293 or 215-526-2167; e-mail:

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About NewAge Industries and AdvantaPure The AdvantaPure division of NewAge Industries is ISO 9001:2015 certified and specializes in high purity tubing, hose, Single-Use process tubing manifolds, BioClosure® container closure systems, and other molded components for the pharmaceutical, biopharm, biomedical, food, beverage and chemical industries. Products are manufactured, stored and shipped using methods that ensure product purity.

In business since 1954, NewAge Industries manufactures plastic and rubber tubing in reinforced and unreinforced styles. NewAge Industries maintains a large inventory of tubing and fittings for its core product lines, provides custom extrusion and fabrication capabilities, and services customers worldwide. Automated product identification systems, including gamma-stable RFID tags and labels, are offered by NewAge’s Verigenics® division. In 2006, NewAge initiated an ESOP (Employee Stock Ownership Plan) for the benefit of both its employees and customers.